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aor 012  (Alomone Labs)


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    Structured Review

    Alomone Labs aor 012
    Aor 012, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/anti+kappa+opioid+receptor/Anti-%CE%BA-Opioid+Receptor+(OPRK1)+(extracellular)+Antibody/pm40586679-60-17-18
    Average 93 stars, based on 2 article reviews
    aor 012 - by Bioz Stars, 2026-10
    93/100 stars

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    Related Articles

    Immunohistochemical staining:

    Article Title: Synergic Effect of Botulinum Toxin Type A and Triamcinolone Alleviates Scar Pruritus by Modulating Epidermal Hyperinnervation: A Preliminary Report.
    Article Snippet: Background: Patients often experience scar-related pruritus, which adversely affects quality of life.. Triamcinolone acetonide (TAC) is widely used to treat pathologic scars, and botulinum toxin type-A (BTX-A) reportedly improves scarring and associated discomfort.. Objectives: The aim of this study was to investigate the clinical efficacy of combining TAC and BTX-A to reduce scar itch; potential mechanisms were investigated via an animal model. Methods: For the clinical study, each scar on a patient was divided into 2 equal parts, with one part receiving TAC/BTX-A and the other TAC alone.

    Staining:

    Article Title: Synergic Effect of Botulinum Toxin Type A and Triamcinolone Alleviates Scar Pruritus by Modulating Epidermal Hyperinnervation: A Preliminary Report.
    Article Snippet: Background: Patients often experience scar-related pruritus, which adversely affects quality of life.. Triamcinolone acetonide (TAC) is widely used to treat pathologic scars, and botulinum toxin type-A (BTX-A) reportedly improves scarring and associated discomfort.. Objectives: The aim of this study was to investigate the clinical efficacy of combining TAC and BTX-A to reduce scar itch; potential mechanisms were investigated via an animal model. Methods: For the clinical study, each scar on a patient was divided into 2 equal parts, with one part receiving TAC/BTX-A and the other TAC alone.



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    Image Search Results


    Role of kappa-opioid receptor in human sperm physiology. Effect of 1 and 60 min U50488H (1 μm) (Kappa-opioid receptor agonist) treatments in human sperm motility, capacitation and acrosome reaction. A,, Immunoblotting assays showing the expression of the phosphorylated substrates of protein kinase C following 1 and 60 min U50488H treatment. n, = 3. (**p, < 0.01 versus, Control). B,, Motility assays using the CASA (Computer Assisted Sperm Analyzer) system for the study of 1 and 60 minutes U50488H treatment in the progressive, nonprogressive, immotile and hyperactive motilities. X axis shows the motility types measured in the study and the Y axis represents the normalized data of the % of motile spermatozoa. The normalization was performed using the untreated samples (Control). n, = 8. (*p, < 0.05 and **p, < 0.01 versus, Control). C,, Immunoblotting assays for the study of U50488H in human sperm capacitation using the anti-pTyr antibody. D,, Flow citometry experiments for the study of U50488H in the human sperm acrosome reaction. X axis shows the different treatments used in the study and the Y axis represents the normalized data of the % acrosome reacted spermatozoa. The normalization was performed using the untreated samples and the acrosome reacted samples. The progesterone was used as the positive control of the acrosome reaction. n, = 7. (**p, < 0.01 versus, Control) AR: acrosome reaction. P-subtrates PKC: Phosphorylated substrates of PKC.

    Journal: Molecular & Cellular Proteomics : MCP

    Article Title: Phosphoproteomic and Functional Analyses Reveal Sperm-specific Protein Changes Downstream of Kappa Opioid Receptor in Human Spermatozoa *

    doi: 10.1074/mcp.RA118.001133

    Figure Lengend Snippet: Role of kappa-opioid receptor in human sperm physiology. Effect of 1 and 60 min U50488H (1 μm) (Kappa-opioid receptor agonist) treatments in human sperm motility, capacitation and acrosome reaction. A,, Immunoblotting assays showing the expression of the phosphorylated substrates of protein kinase C following 1 and 60 min U50488H treatment. n, = 3. (**p, < 0.01 versus, Control). B,, Motility assays using the CASA (Computer Assisted Sperm Analyzer) system for the study of 1 and 60 minutes U50488H treatment in the progressive, nonprogressive, immotile and hyperactive motilities. X axis shows the motility types measured in the study and the Y axis represents the normalized data of the % of motile spermatozoa. The normalization was performed using the untreated samples (Control). n, = 8. (*p, < 0.05 and **p, < 0.01 versus, Control). C,, Immunoblotting assays for the study of U50488H in human sperm capacitation using the anti-pTyr antibody. D,, Flow citometry experiments for the study of U50488H in the human sperm acrosome reaction. X axis shows the different treatments used in the study and the Y axis represents the normalized data of the % acrosome reacted spermatozoa. The normalization was performed using the untreated samples and the acrosome reacted samples. The progesterone was used as the positive control of the acrosome reaction. n, = 7. (**p, < 0.01 versus, Control) AR: acrosome reaction. P-subtrates PKC: Phosphorylated substrates of PKC.

    Article Snippet: After, samples were incubated overnight at 4°C with the polyclonal rabbit anti-Kappa opioid receptor (ABN456, Millipore) (1:500).

    Techniques: Western Blot, Expressing, Positive Control